The VPS33B antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to VPS33B, and VPS33B late endosome and lysosome associated. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, and Zebrafish/Fish antigen. The VPS33B antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages(PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity(PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies(MVBs) promoting MVBs maturation in megakaryocytes(By similarity)